How does
the problem begin?
·
Melanocytes (the cells responsible for forming melanin, and also
melanomas) become much more active when excited by these photons. This means
that when exposed to the sun, the melanocytes have greater cellular activity,
and therefore, the skin tone darkens due to the production of excess melanin.
·
This is generated as a protective reaction. While larger melanocytes are
in the skin, the greater the barrier present to these UV rays that could affect
the body. However, this constant exposure can affecteventuallythe functioning
of these cells. Their destruction or excessive activity can generate serious
consequences, and among them is their abnormal reproduction.
·
This is due to the high capacity of renewal of the epithelial cells of
the most superficial layer of the skin. The destruction of the melanocyte can
affect it at the genetic level, within the bases that make up its DNA, and
generate that inappropriate orders are produced that lead the cells to
uncontrolled reproduction.
In the case of a nodular
melanoma, these cells carry out this process much more rapidly. This is one
of the most delicate cases that can be treated, and usually they are inherent
in genetics, but in a high percentage they are a consequence of the described
problem.
The opposite happens in a subungual melanoma, where the causes of appearance are usually
others. In fact, they appear in a single one of low exposure to the sun (under
the nails) and in people of dark complexion, which gives clear indications of
other origins.
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